muscular dystrophy

muscular dystrophy
A group of diseases characterized by progressive degeneration and/or loss of muscle fibres without nervous system involvement. All or nearly all of them have a hereditary origin but details of the type of genetic defect and of the prognosis for the disease vary from type to type. Duchenne MD (pseudohypertrophic MD) is the most common form. It is due to a sex-linked recessive allele and this is expressed as an absence of the protein dystrophin; the disease in boys shows extensive but insufficient muscle fibre reformation from satellite cells.

Dictionary of molecular biology. 2004.

Игры ⚽ Поможем сделать НИР

Look at other dictionaries:

  • Muscular dystrophy — Classification and external resources ICD 10 G71.0 ICD 9 359.0 …   Wikipedia

  • muscular dystrophy — n any of a group of hereditary diseases characterized by progressive wasting of muscles called also progressive muscular dystrophy see BECKER MUSCULAR DYSTROPHY, DUCHENNE MUSCULAR DYSTROPHY * * * a group of muscl …   Medical dictionary

  • muscular dystrophy — noun uncount a serious illness in which your muscles gradually become weaker …   Usage of the words and phrases in modern English

  • muscular dystrophy — ► NOUN ▪ a hereditary condition marked by progressive weakening and wasting of the muscles …   English terms dictionary

  • muscular dystrophy — n. a chronic, noncontagious disease characterized by a progressive wasting of the muscles …   English World dictionary

  • muscular dystrophy — Pathol. a hereditary disease characterized by gradual wasting of the muscles with replacement by scar tissue and fat, sometimes also affecting the heart. [1865 70] * * * Inherited disease that causes progressive weakness in the skeletal (and… …   Universalium

  • muscular dystrophy — noun any of several hereditary diseases of the muscular system characterized by weakness and wasting of skeletal muscles (Freq. 2) • Syn: ↑dystrophy • Hypernyms: ↑genetic disease, ↑genetic disorder, ↑genetic abnormality, ↑genetic defect …   Useful english dictionary

  • muscular dystrophy — a group of muscle diseases, marked by weakness and wasting of selected muscles, in which there is a recognizable pattern of inheritance. The affected muscle fibres degenerate and are replaced by fatty tissue. The muscular dystrophies are… …   The new mediacal dictionary

  • muscular dystrophy — noun Date: 1886 any of a group of hereditary diseases characterized by progressive wasting of muscles compare Becker muscular dystrophy, Duchenne muscular dystrophy …   New Collegiate Dictionary

  • muscular dystrophy — [[t]mʌ̱skjʊlə(r) dɪ̱strəfi[/t]] N UNCOUNT Muscular dystrophy is a serious disease in which your muscles gradually weaken …   English dictionary

  • Muscular Dystrophy Canada — (MDC) (French: Dystrophie musculaire Canada) is a non profit organization that strives to find a cure for neuromuscular disorders. Founded in 1954 as Muscular Dystrophy Association of Canada, volunteers and staff nation wide have helped to… …   Wikipedia

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”